Never heard of anything like that but I should think it is highly possible.
Did you connect the stick to the front USB slots or the ones at the back?
If you connected it to the front then it is worth looking in your manual and making sure that the connector has been plugged in the right way round.
Here is the manual for the Soyo Sy-P4VGA -
http://www.soyousa.com/dl/manuals/p4/mp4vga10.pdf