In my experience I'd say it is more a case of using another activation count, but you need to be careful with the Windows Installation procedure. If you select the wrong option you could wipe your existing files.
I suggest if you do go with a new motherboard and/or a new
CPU that you first iron out exactly what the Windows Installation procedure is so that doesn't happen.
There is probably a procedure written on the Internet that will walk you through it. There might even be one here in the PCHF database. When you are ready, I'm sure someone here will be able to help you.
Good Luck...