I think that posting my HijackThis log will help, but if it isn't enough, please let me know. My computer will randomly make a C:\Uploads folder that puts random files in it until it's like 3.3GB. I don't have any P2P software, but it looks like that's what it's for. Sometimes there are "loader" problems on XP Pro login, and logging in never completes. I can tell there is tons of spyware/adware on my PC but am having a tough time with removal. I am a fairly experienced computer person and can work with the registry, but I thought I'd get some professional advice. Thanks in advance!

Logfile of HijackThis v1.99.1
Scan saved at 6:11:09 PM, on 6/17/2005
Platform: Windows XP (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 (6.00.2600.0000)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\csrss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\TGTSoft\StyleXP\StyleXPService.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\wdfmgr.exe
C:\Program Files\Common Files\Softwin\BitDefender Communicator\xcommsvr.exe
C:\Program Files\Common Files\Softwin\BitDefender Scan Server\bdss.exe
E:\BitDefender8\vsserv.exe
C:\WINDOWS\Explorer.EXE
E:\BitDefender8\bdoesrv.exe
E:\BitDefender8\bdswitch.exe
E:\iTunes\iTunesHelper.exe
E:\Spyware Doctor\swdoctor.exe
C:\Program Files\iPod\bin\iPodService.exe
E:\Rainlendar\Rainlendar.exe
C:\WINDOWS\System32\devldr32.exe
E:\BitDefender8\bdmcon.exe
C:\WINDOWS\System32\wuauclt.exe
E:\AIM\aim.exe
E:\Ace Utilities\au.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\Documents and Settings\Dylan\Desktop\hijackthis\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = about:blank
R3 - URLSearchHook: (no name) - _{CFBFAE00-17A6-11D0-99CB-00C04FD64497} - (no file)
O2 - BHO: BHObj Class - {00000010-6F7D-442C-93E3-4A4827C2E4C8} - C:\WINDOWS\nem220.dll
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - E:\Adobe\ActiveX\AcroIEHelper.dll
O2 - BHO: SABHO - {21B4ACC4-8874-4AEC-AEAC-F567A249B4D4} - c:\program files\180searchassistant\salmhook.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - E:\Spybot - Search & Destroy\SDHelper.dll
O2 - BHO: PCTools Site Guard - {5C8B2A36-3DB1-42A4-A3CB-D426709BBFEB} - E:\SPYWAR~1\tools\iesdsg.dll
O2 - BHO: PCTools Browser Monitor - {B56A7D7D-6927-48C8-A975-17DF180C71AC} - E:\SPYWAR~1\tools\iesdpb.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O4 - HKLM\..\Run: [NeroCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKLM\..\Run: [EPSON Stylus Photo R300 Series] C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S4I2F 1.EXE /P30 "EPSON Stylus Photo R300 Series" /O6 "USB001" /M "Stylus Photo R300"
O4 - HKLM\..\Run: [BDMCon] E:\BitDefender8\\bdmcon.exe
O4 - HKLM\..\Run: [BDOESRV] E:\BitDefender8\\bdoesrv.exe
O4 - HKLM\..\Run: [BDNewsAgent] E:\BitDefender8\\bdnagent.exe
O4 - HKLM\..\Run: [BDSwitchAgent] E:\BitDefender8\\bdswitch.exe
O4 - HKLM\..\Run: [Openwares LiveUpdate] C:\Program Files\LiveUpdate\LiveUpdate.exe
O4 - HKLM\..\Run: [iTunesHelper] E:\iTunes\iTunesHelper.exe
O4 - HKLM\..\Run: [EPSON Stylus Photo R300 Series on ANDY (from ARMADA-E500)] C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S4I2F 1.EXE /P57 "EPSON Stylus Photo R300 Series on ANDY (from ARMADA-E500)" /O5 "TS001" /M "Stylus Photo R300"
O4 - HKLM\..\Run: [winupdate] C:\Program Files\winupdate\winupdate.exe /auto
O4 - HKLM\..\Run: [p2pnetworking] p2pnetworking.exe
O4 - HKLM\..\Run: [Media Access] C:\Program Files\Media Access\MediaAccK.exe
O4 - HKLM\..\RunServices: [p2pnetworking] p2pnetworking.exe
O4 - HKCU\..\Run: [SetDefaultMIDI] MIDIDef.exe
O4 - HKCU\..\Run: [Spyware Doctor] "E:\Spyware Doctor\swdoctor.exe" /Q
O4 - Startup: Rainlendar.lnk = E:\Rainlendar\Rainlendar.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O9 - Extra button: SideFind - {10E42047-DEB9-4535-A118-B3F6EC39B807} - C:\WINDOWS\System32\shdocvw.dll
O9 - Extra button: Spyware Doctor - {2D663D1A-8670-49D9-A1A5-4C56B4E14E84} - E:\SPYWAR~1\tools\iesdpb.dll
O9 - Extra button: EmpirePoker - {77E68763-4284-41d6-B7E7-B6E1F053A9E7} - C:\WINDOWS\System32\shdocvw.dll
O9 - Extra 'Tools' menuitem: EmpirePoker - {77E68763-4284-41d6-B7E7-B6E1F053A9E7} - C:\WINDOWS\System32\shdocvw.dll
O9 - Extra button: AIM - {AC9E2541-2814-11d5-BC6D-00B0D0A1DE45} - E:\AIM\aim.exe
O9 - Extra button: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - e:\PartyPoker\PartyPoker.exe
O9 - Extra 'Tools' menuitem: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - e:\PartyPoker\PartyPoker.exe
O9 - Extra button: AbsolutePoker.com - {EFFF8D47-D060-4108-B761-E8EC86622E56} - C:\Documents and Settings\All Users\Start Menu\Programs\Absolute Poker\Absolute Poker.lnk
O9 - Extra 'Tools' menuitem: AbsolutePoker.com - {EFFF8D47-D060-4108-B761-E8EC86622E56} - C:\Documents and Settings\All Users\Start Menu\Programs\Absolute Poker\Absolute Poker.lnk
O15 - Trusted Zone: http://ny.contentmatch.net (HKLM)
O16 - DPF: {0A5FD7C5-A45C-49FC-ADB5-9952547D5715} (Creative Software AutoUpdate) - http://www.creative.com/su/ocx/15009/CTSUEng.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://v5.windowsupdate.microsoft.c...b?1110140481671
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} (HouseCall Control) - http://a840.g.akamai.net/7/840/537/...all/xscan53.cab
O16 - DPF: {99410CDE-6F16-42ce-9D49-3807F78F0287} (ClientInstaller Class) - http://www.180searchassistant.com/180saax.cab
O16 - DPF: {F6ACF75C-C32C-447B-9BEF-46B766368D29} (Creative Software AutoUpdate Support Package) - http://www.creative.com/su/ocx/15010/CTPID.cab
O23 - Service: Adobe LM Service - Unknown owner - C:\Program Files\Common Files\Adobe Systems Shared\Service\Adobelmsvc.exe
O23 - Service: Ati HotKey Poller - ATI Technologies Inc. - C:\WINDOWS\System32\Ati2evxx.exe
O23 - Service: ATI Smart - Unknown owner - C:\WINDOWS\system32\ati2sgag.exe
O23 - Service: BitDefender Scan Server (bdss) - Unknown owner - C:\Program Files\Common Files\Softwin\BitDefender Scan Server\bdss.exe
O23 - Service: FireDaemon Service: ecure (ecure) - Unknown owner - C:\WINDOWS\Temp\FireDaemon.EXE (file missing)
O23 - Service: iPod Service (iPodService) - Apple Computer, Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: StyleXPService - Unknown owner - C:\Program Files\TGTSoft\StyleXP\StyleXPService.exe
O23 - Service: FireDaemon Service: svchost1 (svchost1) - Unknown owner - C:\WINDOWS\Temp\FireDaemon.EXE (file missing)
O23 - Service: BitDefender Virus Shield (VSSERV) - Unknown owner - E:\BitDefender8\vsserv.exe
O23 - Service: BitDefender Communicator (XCOMM) - Softwin - C:\Program Files\Common Files\Softwin\BitDefender Communicator\xcommsvr.exe

Welcome to the forum.

Well, there are certainly a few things in there that you can "fix":

E:\Ace Utilities\au.exe
R3 - URLSearchHook: (no name) - _{CFBFAE00-17A6-11D0-99CB-00C04FD64497} - (no file)
O2 - BHO: BHObj Class - {00000010-6F7D-442C-93E3-4A4827C2E4C8} - C:\WINDOWS\nem220.dll
O4 - HKLM\..\Run: [winupdate] C:\Program Files\winupdate\winupdate.exe /auto
O4 - HKLM\..\Run: [Media Access] C:\Program Files\Media Access\MediaAccK.exe? ?
O9 - Extra button: SideFind - {10E42047-DEB9-4535-A118-B3F6EC39B807} - C:\WINDOWS\System32\shdocvw.dll
O9 - Extra button: EmpirePoker - {77E68763-4284-41d6-B7E7-B6E1F053A9E7} - C:\WINDOWS\System32\shdocvw.dll
O9 - Extra 'Tools' menuitem: EmpirePoker - {77E68763-4284-41d6-B7E7-B6E1F053A9E7} - C:\WINDOWS\System32\shdocvw.dll
O9 - Extra button: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - e:\PartyPoker\PartyPoker.exe
O9 - Extra 'Tools' menuitem: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - e:\PartyPoker\PartyPoker.exe
O9 - Extra button: AbsolutePoker.com - {EFFF8D47-D060-4108-B761-E8EC86622E56} - C:\Documents and Settings\All Users\Start Menu\Programs\Absolute Poker\Absolute Poker.lnk
O9 - Extra 'Tools' menuitem: AbsolutePoker.com - {EFFF8D47-D060-4108-B761-E8EC86622E56} - C:\Documents and Settings\All Users\Start Menu\Programs\Absolute Poker\Absolute Poker.lnk
O15 - Trusted Zone: http://ny.contentmatch.net (HKLM)
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} (HouseCall Control) - http://a840.g.akamai.net/7/840/537/...all/xscan53.cab
O16 - DPF: {99410CDE-6F16-42ce-9D49-3807F78F0287} (ClientInstaller Class) - http://www.180searchassistant.com/180saax.cab
O23 - Service: FireDaemon Service: ecure (ecure) - Unknown owner - C:\WINDOWS\Temp\FireDaemon.EXE (file missing)
O23 - Service: FireDaemon Service: svchost1 (svchost1) - Unknown owner - C:\WINDOWS\Temp\FireDaemon.EXE (file missing)

Also, grab the tools in my sig "Handy Tools" and run them.