Hello
The Registry entries you found appear to be the result of, maybe you searching for the file? They are MRUs (most recently used, which includes searches) and are not a threat, although security scans could well target them.
What you do need to locate and remove are the following. Copy the text to notepad and save it as a Registry (REG) file and execute the script so as to merge into the Registry, automatically removing the offending items...
Code:
REGEDIT4
[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\ShellServiceObjectDelayLoad]
SystemCheck2=-
[-HKEY_CLASSES_ROOT\CLSID\{54645654-2225-4455-44A1-9F4543D34545}]
Also locate the file itself, which will be in either the C:\
WINDOWS or C:\WINDOWS\
System32 directory. You could always try using
[Pocket Killbox] to attempt its removal.
HTH,
M_M