Well first off McAfee (as far as Anti-virus progs go) isn't that good, free ones like AVG (which I use) are far better, or for paid ones, Kapersky is notoriously the best out there hands down. If it gets working again I'd highly recommend changing it. If you can manage to get onto the desktop and use it, please do the prework
Linked here and post the resulting logs and a HiJackThis log in our
[New] HiJackThis Logs forum, if you can't then you may need to open up the PC case, are you comfortable with this and do you have another PC you can put this hard drive in as a slave drive (or second HD)?